- Same nondrowsy, 24-hour relief
- Same gentle, alcohol-free, scent-free mist
- Proven relief for seasonal and perennial allergy symptoms
- Available OTC—delivers the same trusted, prescription-strength relief1
- Does more to block the allergic cascade—works to block 6 key inflammatory mediators—not just histamine*3-6
- Fast onset—24-hour relief7-10
- Starts to act in 2-4 hours in some patients11
- Most patients will have achieved significant relief in 12 hours11
- Maximum benefit achieved in 3-4 days11
- FLONASE® Allergy Relief may help ease the burden on busy medical practices
- Almost 90% of physicians prefer that patients address minor ailments with self-care interventions, including OTC medications, before seeking professional interventions12
- 24-hour relief7-10
- Outperforms the leading nonsedating allergy medicine†13
- Relieving children from their allergies can help improve their quality of life
- Delivers the same trusted prescription-strength relief1
- Works to block 6 key inflammatory mediators—not just histamine*3-6
- Nondrowsy formulation13,14
- The first and only OTC INS to relieve itchy, watery eyes1,2
- Starts to work in 2 to 4 hours in some patients, with maximum benefit in 3 to 4 days11
*Mechanism vs most OTC allergy pills. FLONASE® Allergy Relief acts on multiple inflammatory substances (histamine, prostaglandins, cytokines, tryptases, chemokines, and leukotrienes). The exact number and precise mechanism are unknown.
†Total nasal symptom relief vs 10-mg, single-ingredient loratadine.
- FLONASE Drug Facts Label.
- NASACORT Drug Facts Label.
- Derendorf H, Meltzer EO. Molecular and clinical pharmacology of intranasal corticosteroids: clinical and therapeutic implications. Allergy. 2008;63(10):1292-1300.
- Gelfand EW. Inflammatory mediators in allergic rhinitis. J Allergy Clin Immunol. 2004;114:S135-S138.
- White MV, Kaliner MA. Mediators of allergic rhinitis. J Allergy Clin Immunol. 1992;90(4 II):699-704.
- Bachert C, Geveart P. Effect of intranasal corticosteroids on release of cytokines and inflammatory mediators. Allergy. 1999;54(57):116-123.
- van As A, Bronsky EA, Dockhorn RJ, et al. Once daily fluticasone propionate is as effective for perennial allergic rhinitis as twice daily beclomethasone diproprionate. J Allergy Clin Immunol. 1993;91(6):1146-1154.
- Pedersen B, Dahl R, Richards DH, et al. Once daily fluticasone propionate aqueous nasal spray controls symptoms of most patients with seasonal allergic rhinitis. Allergy. 1995;50(10):794-799.
- Darnell R, Pecoud A, Richards DH. A double-blind comparison of fluticasone propionate aqueous nasal spray, terfenadine tablets and placebo in the treatment of patients with seasonal allergic rhinitis to grass pollen. Clin Exp Allergy. 1994;24(12):1144-1150.
- LaForce CF, Dockhorn RJ, Findlay SR, et al. Fluticasone propionate: an effective alternative treatment for seasonal allergic rhinitis in adults and adolescents. J Fam Pract. 1994;38(2):145-152.
- Meltzer EO, Rickard KA, Westlund RE, Cook CK. Onset of therapeutic effect of fluticasone propionate aqueous nasal spray. Ann Allergy Asthma Immunol. 2001;86(3):286-291.
- Consumer Healthcare Products Association. Your health at hand. Available at http://www.yourhealthathand.org/images/uploads/YHH_Key_Findings.pdf. Accessed April 26, 2016.
- Ratner PH, van Bavel JH, Martin BG, et al. A comparison of the efficacy of fluticasone propionate aqueous nasal spray and loratadine, alone and in combination, for the treatment of seasonal allergic rhinitis. J Fam Pract. 1998;47(2):118-125.
- Mansfield LE, Posey CR. Daytime sleepiness and cognitive performance improve in seasonal allergic rhinitis treated with intranasal fluticasone propionate. Allergy Asthma Proc. 2007;28(2):226-229.